Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.60 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.60 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.60 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704363 | 0.85 | ACHE (0.60) | ACHESIGMAR1APAF1GRIN1GRIN2A | |
| SCHEMBL30704375 | 0.85 | ACHE (0.60) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL16335515 | 0.84 | SIGMAR1 (0.68) | ACHESIGMAR1APAF1GRIN1GRIN2A | |
| SCHEMBL30704338 | 0.82 | ACHE (0.70) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL2186097 | 0.82 | L3MBTL1 (0.70) | ACHESIGMAR1 | |
| SCHEMBL27246711 | 0.81 | ACHE (0.63) | ACHESIGMAR1APAF1 | |
| SCHEMBL30704370 | 0.81 | SIGMAR1 (0.70) | ACHESIGMAR1 | |
| Carvotroline SCHEMBL29710918 | 0.81 | SIGMAR1 (0.88) | ACHESIGMAR1 | |
| SCHEMBL30704364 | 0.81 | ACHE (0.54) | ACHESIGMAR1GRIN1GRIN2AGRIN2D | |
| Carvotroline SCHEMBL350602 | 0.81 | SIGMAR1 (0.88) | ACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |