Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6424517 | 0.87 | — | — | |
| SCHEMBL3585545 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2294091 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL8876177 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6196264 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2761848 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL668569 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL3277379 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2283898 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL852092 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482664-C | 1,5-disubstituted-3,4-dihydro-1H-pyrimido [4,5-D] pyrimidi-2-one compounds and their use in treating CSBP/P38 kinase mediated diseases | SMITHKLINE BEECHAM CORP (US) | 2009-04-29 | — | — | CN | claimed |
| CN-114409585-A | 2-oxopyrrolidine derivatives, process for preparing the same and process for preparing intermediates | 凯莱英医药集团（天津）股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| WO-2015178663-A1 | AN IMPROVED MANUFACTURING METHOD OF ZABOFLOXACIN | DONG WHA PHARM. CO., LTD. (KR) | 2015-11-26 | — | — | WO | disclosed |
| EP-2018792-B1 | SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES | WOCKHARDT LTD (IN) | 2015-09-16 | — | — | EP | disclosed |
| US-20130296569-A1 | PROCESS FOR THE PREPARATION OF PHOSPHORIC ACID MONO-(1--4-METHOXYMETHYL-PIPERIDIN-4-YL) ESTER | PATIL VIJAYKUMAR JAGDISHWAR (IN) | 2013-11-07 | — | — | US | disclosed |
| EP-2635589-A1 | PROCESS FOR THE PREPARATION OF PHOSPHORIC ACID MONO- (L-{4- [(S) -5- (ACETYLAMINOMETHYL) - 2 - OXO - OXAZOLIDIN- 3 - YL]- 2, 6 - DIFLUOROPHENYL} - 4 -METHOXYMETHYLPIPERIDIN- 4 - YL) ESTER | Wockhardt Limited (IN) | 2013-09-11 | — | — | EP | disclosed |
| US-8217058-B2 | Substituted piperidino phenyloxazolidinones | WOCKHARDT LTD. (IN) | 2012-07-10 | — | — | US | disclosed |
| WO-2012059823-A1 | PROCESS FOR THE PREPARATION OF PHOSPHORIC ACID MONO- (L-{4- [(S) -5- (ACETYLAMINOMETHYL) - 2 - OXO - OXAZOLIDIN- 3 - YL] - 2, 6 - DIFLUOROPHENYL} - 4 -METHOXYMETHYLPIPERIDIN- 4 - YL) ESTER | WOCKHARDT LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |
| CN-102106184-A | Substituted piperidino phenyloxazolidinones | WOCKHARDT LTD | 2011-06-22 | — | — | CN | disclosed |
| US-20100056581-A1 | Substituted Piperidino Phenyloxazolidinones | PATEL MAHESH VITHALBHAI | 2010-03-04 | — | — | US | disclosed |
| EP-2018792-A2 | SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES | Wockhardt Limited (IN) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007132314-A2 | SUBSTITUTED PIPERIDINO PHENYLOXAZOLIDINONES | WOCKHARDT LTD (IN) | 2007-11-22 | — | — | WO | disclosed |
| US-7208567-B2 | Polymer compound and polymer light emitting device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-24 | — | — | US | disclosed |
| CN-1603323-A | Process for preparing 5-[[4-[2-(5- ethyl-2- pyridyl) ethoxy] phenyl] methyl]-2,4- thiazolidinedione | SHANDONG A & T PHARM CO LTD (CN) | 2005-04-06 | — | — | CN | disclosed |
| US-20040002576-A1 | Polymer compound and polymer light emitting device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-01-01 | — | — | US | disclosed |
| CN-1058010-C | Novel quinoline carboxylic acid derivatives having 7-(4-aminomethyl-3-oxime) pyrrolidine substituent and processes for preparing thereof | LG CHEMICAL LTD (KR) | 2000-11-01 | — | — | CN | disclosed |
| CN-1114959-A | Novel quinoline carboxylic acid derivatives having 7-(4-aminomethyl-3-oxime) pyrrolidine substituent and processes for preparing thereof | LG CHEMICAL LTD (KR) | 1996-01-17 | — | — | CN | disclosed |