Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.37 |
| ▸ | HTR3A | P46098 | 6/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27249476 | 0.80 | NR4A2 (0.49) | HTR3AALDH1A1KMT2ACHRM1POLB | |
| SCHEMBL27249577 | 0.76 | HTR3A (0.48) | CNR1HTR3AALDH1A1 | |
| SCHEMBL2439783 | 0.73 | POLB (0.47) | CNR1MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL27249524 | 0.71 | CACNA1H (0.46) | CNR1HTR3AMEN1KMT2A | |
| SCHEMBL4002045 | 0.71 | POLB (0.45) | CNR1MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL7498303 | 0.70 | POLB (0.41) | CNR1MEN1ALDH1A1KMT2ACHRM1 | |
| SCHEMBL6593085 | 0.69 | ALDH1A1 (0.45) | CNR1P2RX7MEN1ALDH1A1KMT2A | |
| SCHEMBL1020294 | 0.68 | P2RX7 (0.51) | P2RX7KMT2ACHRM1 | |
| SCHEMBL10321556 | 0.68 | MEN1 (0.50) | P2RX7MEN1KMT2A | |
| SCHEMBL17572988 | 0.68 | MEN1 (0.46) | PRMT5MEN1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077391-A1 | THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | UNIVERSITE DE MONTREAL (CA) | 2024-04-18 | — | — | WO | disclosed |