SCHEMBL27250397

SCHEMBL27250397

CN[C@H](CS)C(=O)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ PTGS2 P35354 1/20 0.40
▸ THPO P40225 1/20 0.40
▸ RECQL P46063 1/20 0.40
▸ BLM P54132 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ ENPEP Q07075 3/20 0.38
▸ ANPEP P15144 1/20 0.38
▸ FOLH1 Q04609 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14091445 1.00 ACE (0.41) ACEKDM4EMAPTTHRBALOX15
SCHEMBL20154135 0.82 ANPEP (0.35) ACEENPEPANPEP
SCHEMBL13213426 0.79 ACE (0.39) ACEKDM4EMAPTTHRBALOX15
SCHEMBL24494714 0.79 ACE (0.39) ACEKDM4EMAPTTHRBALOX15
SCHEMBL27250345 0.79 ACE (0.39) ACEKDM4EMAPTTHRBALOX15
SCHEMBL18435207 0.78 ALDH1A1 (0.32) —
SCHEMBL22696774 0.78 ALDH1A1 (0.32) —
SCHEMBL24153005 0.78 ALDH1A1 (0.32) —
SCHEMBL18880094 0.78 TGFBR1 (0.33) —
SCHEMBL20622862 0.77 KDM4E (0.63) ACEKDM4EMAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209382-A1 NANOPARTICLES AND BIOTEMPLATES WITH TUNABLE LENGTH AND METHODS OF MANUFACTURING THE SAME UNIVERSITY OF DELAWARE 2024-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209382-A1 NANOPARTICLES AND BIOTEMPLATES WITH TUNABLE LENGTH AND METHODS OF MANUFACTURING THE SAME RNGTT, HBS1L, BROX ACE 1147/4885KDM4E 3151/4885MAPT 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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