Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 4/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29998947 | 0.78 | ESR2 (0.44) | HSD17B1HSD17B2ESR2ESR1PTGS2 | |
| SCHEMBL27087469 | 0.78 | ESR2 (0.44) | HSD17B1HSD17B2ESR2ESR1PTGS2 | |
| SCHEMBL25211145 | 0.62 | ESR1 (0.46) | HSD17B1HSD17B2ESR2ESR1PTGS2 | |
| SCHEMBL30500261 | 0.62 | ESR1 (0.46) | HSD17B1HSD17B2ESR2ESR1PTGS2 | |
| SCHEMBL25202116 | 0.61 | ESR2 (0.42) | HSD17B1HSD17B2ESR2ESR1CSNK2A1 | |
| SCHEMBL29911026 | 0.61 | ESR2 (0.77) | ALOX5HSD17B1HSD17B2ESR2ESR1 | |
| SCHEMBL28202577 | 0.61 | ESR2 (0.77) | ALOX5HSD17B1HSD17B2ESR2ESR1 | |
| SCHEMBL278316 | 0.61 | ESR2 (0.77) | ALOX5HSD17B1HSD17B2ESR2ESR1 | |
| SCHEMBL8040099 | 0.60 | SMN1; SMN2 (0.43) | ALOX5MEN1KMT2A | |
| SCHEMBL25202713 | 0.60 | MAPT (0.60) | ESR2ESR1PTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208959-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208959-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208959-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | ALOX5 1089/4885PTGES 878/4885HSD17B1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.