Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.47 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17096987 | 0.86 | HDAC1 (0.44) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL17102229 | 0.81 | HDAC1 (0.43) | HDAC1ESR2NR1H2ABHD6DDB1 | |
| SCHEMBL27257521 | 0.79 | L3MBTL1 (0.53) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL30564186 | 0.79 | PIM1 (0.46) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL23496956 | 0.79 | L3MBTL1 (0.53) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL30719630 | 0.79 | L3MBTL1 (0.53) | L3MBTL1PIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL31070535 | 0.79 | ABHD6 (0.63) | HDAC1ESR2NR1H2ABHD6DDB1 | |
| SCHEMBL31070528 | 0.78 | HDAC1 (0.44) | HDAC1ESR2NR1H2ABHD6DDB1 | |
| SCHEMBL31070534 | 0.78 | HDAC1 (0.44) | HDAC1ESR2NR1H2ABHD6DDB1 | |
| SCHEMBL5871186 | 0.78 | L3MBTL1 (0.51) | L3MBTL1PIM1MARK3MAP4K2CAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |