SCHEMBL2725945

SCHEMBL2725945

C=C(C)COc1ccc(C)cc1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
TSHR P16473 3/20 0.41
POLB P06746 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
HSD17B10 Q99714 2/20 0.40
LMNA P02545 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPK1 P28482 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTGDR2 Q9Y5Y4 2/20 0.38
HTR2B P41595 2/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
USP2 O75604 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6710041 0.85 ALDH1A1 (0.40) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL31388179 0.83 PTGDR2 (0.56) KDM4ETSHRPOLBSMN1; SMN2L3MBTL1
SCHEMBL29377861 0.80 GPR174 (0.40) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL28076 0.80 GPR174 (0.40) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL570810 0.78 GPR174 (0.39) KDM4EALDH1A1MAPTHPGDKMT2A
Ammonia Solution, Strong SCHEMBL6716826 0.78 GPR174 (0.39) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL570808 0.78 GPR174 (0.39) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL8161005 0.77 SMN1; SMN2 (0.51) KDM4EALDH1A1MAPTHPGDKMT2A
SCHEMBL4539460 0.77 POLB (0.51) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL17488866 0.77 KMT2A (0.45) HPGDKMT2AMEN1TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714064-B2 Controllable and rapid solubility rate of water-soluble polymeric films HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2010-05-11 US claimed
US-20080097029-A1 CONTROLLABLE AND RAPID SOLUBILITY RATE OF WATER-SOLUBLE POLYMERIC FILMS HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2008-04-24 US claimed
US-20040204543-A1 Controllable and rapid solubility rate of water-soluble polymeric films YANG THOMAS P (CA) 2004-10-14 US claimed
US-10113099-B2 High pressure high temperature (HPHT) aqueous drilling mud composition and process for preparing the same ISP INVESTMENTS LLC (US) 2018-10-30 US disclosed
US-10023782-B2 Salt-tolerant, thermally-stable rheology modifiers ISP INVESTMENTS LLC (US) 2018-07-17 US disclosed
US-20170335162-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS HERCULES LLC 2017-11-23 US disclosed
US-9611416-B2 Salt-tolerant, thermally-stable rheology modifiers ISP INVESTMENTS LLC (US) 2017-04-04 US disclosed
US-20150368538-A1 A NOVEL HIGH PRESSURE HIGH TEMPERATURE (HPHT) AQUEOUS DRILLING MUD COMPOSITION AND PROCESS FOR PREPARING THE SAME ISP INVESTMENTS INC. (US) 2015-12-24 US disclosed
WO-2014133824-A1 A NOVEL HIGH PRESSURE HIGH TEMPERATURE (HPHT) AQUEOUS DRILLING MUD COMPOSITION AND PROCESS FOR PREPARING THE SAME ISP INVESTMENTS INC. (US) 2014-09-04 WO disclosed
US-20130324443-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS ISP INVESTMENTS INC. (US) 2013-12-05 US disclosed
WO-2013162902-A1 SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER ISP INVESTMENTS INC (US) 2013-10-31 WO disclosed
WO-2013138156-A1 SYNTHESIS AND APPLICATION OF HIGH PRESSURE HIGH TEMPERATURE FLUID LOSS ADDITIVE AND RHEOLOGY STABILIZER ISP INVESTMENTS INC. (US) 2013-09-19 WO disclosed
WO-2012061147-A1 SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS ISP INVESTMENTS INC. (US) 2012-05-10 WO disclosed
US-7714064-B2 Controllable and rapid solubility rate of water-soluble polymeric films HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2010-05-11 US disclosed
US-20080097029-A1 CONTROLLABLE AND RAPID SOLUBILITY RATE OF WATER-SOLUBLE POLYMERIC FILMS HARBIN LONGYI NEW MATERIAL TECHNOLOGY CO. LTD. (CN) 2008-04-24 US disclosed
US-20040204543-A1 Controllable and rapid solubility rate of water-soluble polymeric films YANG THOMAS P (CA) 2004-10-14 US disclosed