SCHEMBL6710041

SCHEMBL6710041

C=C(C)COc1ccc(C)cc1S(=O)(=O)[O-].[Na+]

nearest known ligand 0.40

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A known ✓ P27815 1/20 0.37
PDE4B known ✓ Q07343 1/20 0.37
PDE4C known ✓ Q08493 1/20 0.37
PDE4D known ✓ Q08499 1/20 0.37
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
TSHR P16473 3/20 0.39
POLB P06746 2/20 0.39
SMN1; SMN2 Q16637 5/20 0.39
HSD17B10 Q99714 2/20 0.39
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
HTR2B P41595 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2725945 0.85 KDM4E (0.41) ALDH1A1KDM4EMAPTHPGDKMT2A
SCHEMBL31388199 0.84 PTGDR2 (0.40) ALDH1A1HPGDKMT2AMEN1TSHR
SCHEMBL570809 0.81 ALDH1A1 (0.39) ALDH1A1KDM4EMAPTHPGDKMT2A
SCHEMBL6712770 0.78 LMNA (0.49) ALDH1A1KDM4EMAPTHPGDTSHR
Potassium Ion SCHEMBL6714454 0.78 ALDH1A1 (0.39) ALDH1A1KDM4EMAPTHPGDKMT2A
SCHEMBL6712920 0.78 ALDH1A1 (0.39) ALDH1A1KDM4EMAPTHPGDKMT2A
SCHEMBL6716847 0.77 ALDH1A1 (0.40) ALDH1A1KDM4EMAPTHPGDKMT2A
SCHEMBL6714462 0.75 LMNA (0.49) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL8161005 0.75 SMN1; SMN2 (0.51) ALDH1A1KDM4EMAPTHPGDKMT2A
SCHEMBL6712838 0.74 POLB (0.41) ALDH1A1KDM4EMAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6740722-B2 Low density acrylic fiber SOLUTIA INC. 2004-05-25 US disclosed
US-20030057593-A1 Low density acrylic fiber ASCEND PERFORMANCE MATERIALS OPERATIONS LLC 2003-03-27 US disclosed
WO-1999058586-A1 ACRYLIC FIBER POLYMER PRECURSOR AND FIBER SOLUTIA INC. (US) 1999-11-18 WO disclosed