SCHEMBL2725992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15339806	0.88	CES2 (0.52)	CES2ALDH1A1KMT2AMEN1NPC1
	SCHEMBL15334134	0.86	NPC1 (0.66)	CES2KMT2ANPC1RAB9AGAA
	SCHEMBL4446674	0.84	PLAAT3 (0.50)	CES2ALDH1A1KMT2AMEN1NPC1
	SCHEMBL4437059	0.82	CES2 (0.74)	CES2ALDH1A1KMT2AMEN1NPC1
	SCHEMBL22981993	0.82	KMT2A (0.56)	CES2ALDH1A1KMT2ANPC1RAB9A
	SCHEMBL4435233	0.82	KMT2A (0.62)	KMT2AGAAMAPTHCRTR1LMNA
	SCHEMBL2725306	0.81	CES2 (0.54)	CES2ALDH1A1KMT2AMEN1GAA
	SCHEMBL15339807	0.80	CES2 (0.52)	CES2ALDH1A1KMT2AMEN1NPC1
	SCHEMBL1838515	0.79	HCRTR1 (0.61)	KMT2AGLAHCRTR1
	SCHEMBL2726712	0.78	RAB9A (0.55)	CES2ALDH1A1NPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.