Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 4/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726428 | 0.88 | NAA50 (0.39) | NAA50HSD11B1POLBTRPV1CPT2 | |
| SCHEMBL2725263 | 0.85 | NAA50 (0.42) | NAA50HSD11B1POLBTRPV1CPT2 | |
| SCHEMBL2727029 | 0.85 | HSD11B1 (0.37) | NAA50HSD11B1POLBTRPV1CPT2 | |
| SCHEMBL166240 | 0.83 | TRPV1 (0.42) | NAA50POLBTRPV1CPT2CPT1A | |
| SCHEMBL166241 | 0.83 | TRPV1 (0.42) | NAA50POLBTRPV1CPT2CPT1A | |
| SCHEMBL6466955 | 0.82 | BAZ2A (0.41) | NAA50POLBTRPV1CPT2CPT1A | |
| SCHEMBL6464489 | 0.82 | POLB (0.39) | NAA50POLBTRPV1CPT2CPT1A | |
| SCHEMBL2725418 | 0.81 | CPT2 (0.42) | NAA50HSD11B1POLBTRPV1CPT2 | |
| SCHEMBL10290636 | 0.81 | BAZ2A (0.42) | NAA50POLBTRPV1CPT2CPT1A | |
| SCHEMBL165849 | 0.81 | ROCK2 (0.49) | NAA50POLBTRPV1CPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |