Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27264565 | 0.76 | CTSA (0.36) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL27264852 | 0.76 | KDM4E (0.38) | ALDH1A1HSD17B10 | |
| SCHEMBL27263848 | 0.73 | — | — | |
| SCHEMBL11344359 | 0.67 | L3MBTL1 (0.33) | TP53POLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27264511 | 0.66 | HPGD (0.46) | TP53POLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27264036 | 0.65 | APEX1 (0.31) | SMN1; SMN2MAPTAPEX1RAB9A | |
| SCHEMBL10403230 | 0.65 | GAA (0.54) | POLBALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL27264189 | 0.64 | ALDH1A1 (0.33) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL16797589 | 0.63 | LMNA (0.43) | TP53POLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL17824102 | 0.63 | P2RX3 (0.38) | TP53POLBALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1021910-C | LANKACIDIN DERIVATIVES AND PRODUCTION THEREOF | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-08-25 | — | — | CN | disclosed |