Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 5/20 | 0.36 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565872 | 0.87 | GNAO1 (0.41) | GNAO1GBA1SLC6A1GABRA5GABRB2 | |
| SCHEMBL4036508 | 0.82 | NCF1 (0.48) | GNAO1GBA1GNAI3GNAI1 | |
| SCHEMBL27268051 | 0.80 | NCF1 (0.33) | — | |
| SCHEMBL331996 | 0.80 | GBA1 (0.42) | GNAO1GBA1SLC6A1GABRA5GABRB2 | |
| SCHEMBL25047986 | 0.78 | CHRM2 (0.35) | SLC6A4 | |
| SCHEMBL14083889 | 0.78 | CHRM2 (0.35) | SLC6A4 | |
| SCHEMBL24891018 | 0.77 | GBA1 (0.33) | GBA1 | |
| SCHEMBL1241237 | 0.77 | GBA1 (0.41) | GNAO1GBA1SLC6A1GABRA5GABRB2 | |
| SCHEMBL18921635 | 0.77 | GNAO1 (0.33) | GNAO1GBA1 | |
| SCHEMBL16523885 | 0.76 | CHRM5 (0.36) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112692-A1 | CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |