Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK | Q15746 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | Q9HBH1 | 1/20 | 0.32 | |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27272703 | 0.82 | MYLK (0.37) | MYLKNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27270221 | 0.82 | RAB9A (0.39) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL17399090 | 0.75 | MYLK (0.38) | MYLKHDAC4HDAC7HDAC5NPC1 | |
| SCHEMBL27267555 | 0.74 | TP53 (0.31) | ALDH1A1TP53ALOX15HSD17B10 | |
| SCHEMBL27516784 | 0.71 | MAOA (0.41) | NPC1ALDH1A1TP53ALOX15RAB9A | |
| SCHEMBL19675523 | 0.65 | NOX1 (0.44) | HDAC4HDAC7HDAC5GSK3BPDF | |
| SCHEMBL10994406 | 0.65 | MYLK (0.43) | MYLKNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL32662573 | 0.64 | MAOA (0.43) | ALDH1A1SMN1; SMN2GSK3BSLC6A2SLC6A4 | |
| SCHEMBL2500446 | 0.64 | KDM4E (0.50) | HDAC4HDAC7HDAC5ALDH1A1SLC6A2 | |
| SCHEMBL28122052 | 0.63 | NOX1 (0.42) | ALDH1A1RAB9ASMN1; SMN2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020607-C | PROCESS FOR PREPARATION OF BENZOTHIAZINE DERIVS. | HOECHST AG (DE) | 1993-05-12 | — | — | CN | disclosed |
| CN-85101312-A | Process for preparing Benzothiazine derivatives | — | 1987-04-08 | — | — | CN | disclosed |