Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.95 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL7148337 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9227895 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9551477 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL3090 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9232100 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9227913 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9232096 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL21580532 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 | |
| SCHEMBL9228526 | 1.00 | PDE4A (0.95) | PDE4ALMNATDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787368-A | Sorbitan esters and enzymatic process for their preparation | 赢创运营有限公司 | 2022-07-22 | — | — | CN | claimed |
| WO-2022049604-A1 | PROCESS FOR PREPARING REVEFENACIN AND INTERMEDIATES THEROF | CIPLA LIMITED (IN) | 2022-03-10 | — | — | WO | claimed |
| CN-106476379-B | A kind of heat-insulated antifog film of vehicle glass | 东莞市联洲知识产权运营管理有限公司 | 2018-08-17 | — | — | CN | claimed |
| CN-106476379-A | A kind of heat-insulated antifog film of vehicle glass | 东莞市联洲知识产权运营管理有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-106281096-A | A kind of environment friendly heat resistant rupture pressure disc | 东莞市联洲知识产权运营管理有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-103003405-B | Aqueous alkaline cleaning compositions and methods of use thereof | BASF SE (DE) | 2016-04-13 | — | — | CN | claimed |
| CN-103003405-A | Aqueous alkaline cleaning compositions and methods of use thereof | BASF SE | 2013-03-27 | — | — | CN | claimed |
| US-4724099-A | REACTION PRODUCT OF ESTER OF A POLYHYDRIC ALCOHOL AND A BORON-CONTAINING HETEROCYCLIC COMPOUND; EXTREME PRESSURE LUBRICANTS; AUTOMATIC TRANSMISSION FLUIDS | UNION OIL COMPANY OF CALIFORNIA (US) | 1988-02-09 | — | — | US | claimed |
| EP-3515571-B1 | ISOTOPIC COMPOSITIONS | BOTANICAL WATER TECH IP LTD (GB) | 2026-01-07 | — | — | EP | disclosed |
| EP-4655387-A1 | ROOM-TEMPERATURE-STABLE CULTURE MEDIA AND SUPPLEMENTS | Life Technologies Corporation (US) | 2025-12-03 | — | — | EP | disclosed |
| US-20250345435-A1 | ANHYDROUS SODIUM THIOSULFATE AND FORMULATIONS THEREOF | FENNEC PHARMACEUTICALS, INC. (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250346643-A1 | TROPOMYOSIN KINASE RECEPTOR (TRK) LIGANDS AS THERAPEUTICS TO SUPPORT LIVER REGENERATION | UNIV VANDERBILT (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4591939-A2 | FORMULATIONS OF SODIUM THIOSULFATE | Fennec Pharmaceuticals, Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4578506-A2 | FORMULATIONS OF ANHYDROUS SODIUM THIOSULFATE | Fennec Pharmaceuticals, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| CN-103003405-B | Aqueous alkaline cleaning compositions and methods of use thereof | BASF SE (DE) | 2016-04-13 | — | — | CN | disclosed |
| CN-103003405-B | Aqueous alkaline cleaning compositions and methods of use thereof | BASF SE (DE) | 2016-04-13 | — | — | CN | disclosed |
| CN-103003405-A | Aqueous alkaline cleaning compositions and methods of use thereof | BASF SE | 2013-03-27 | — | — | CN | disclosed |
| WO-2012058298-A1 | BIOMARKERS OF REDUCED INSULIN ACTION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-05-03 | — | — | WO | disclosed |
| CN-1211287-C | Method for producing suspensions and powders of indium tin oxide and use thereof | INST NEW MATERIALEN GEM GMBH (DE) | 2005-07-20 | — | — | CN | disclosed |
| CN-1314871-A | Method for producing suspensions and powders based on indium tin oxide and the use thereof | INST NEUE MATERIALEN GEM GMBH (DE) | 2001-09-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346643-A1 | TROPOMYOSIN KINASE RECEPTOR (TRK) LIGANDS AS THERAPEUTICS TO SUPPORT LIVER REGENERATION | HGF, HDGF, NTRK2 | PDE4A 1558/4885LMNA 2803/4885TDP1 1903/4885 |
| US-20250345435-A1 | ANHYDROUS SODIUM THIOSULFATE AND FORMULATIONS THEREOF | TST, MPST, TPMT | PDE4A 4315/4885LMNA 4594/4885TDP1 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.