Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27275411 | 0.83 | BRD4 (0.52) | MAPTTHRBLMNAMEN1KMT2A | |
| SCHEMBL24876653 | 0.81 | LMNA (0.69) | MAPTTHRBLMNAMEN1KMT2A | |
| SCHEMBL31680016 | 0.81 | LMNA (0.69) | MAPTTHRBLMNAMEN1KMT2A | |
| SCHEMBL27275299 | 0.81 | LMNA (0.49) | MAPTTHRBLMNAMEN1KMT2A | |
| SCHEMBL27275406 | 0.79 | LMNA (0.46) | MAPTTHRBLMNAMEN1KMT2A | |
| SCHEMBL27275408 | 0.79 | MAPT (0.52) | MAPTTHRBMEN1KMT2ATP53 | |
| SCHEMBL27275409 | 0.77 | MEN1 (0.41) | MAPTTHRBLMNAMEN1KMT2A | |
| SCHEMBL27275402 | 0.77 | MEN1 (0.43) | MAPTTHRBLMNAMEN1KMT2A | |
| SCHEMBL27275211 | 0.76 | LMNA (0.47) | MAPTTHRBLMNAMEN1KMT2A | |
| SCHEMBL27275617 | 0.75 | MAPT (0.42) | MAPTTHRBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133220-A1 | INHIBITORS OF α-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2024-06-27 | — | — | WO | disclosed |