Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27275406 | 0.78 | LMNA (0.46) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL27275302 | 0.77 | MAPT (0.50) | MEN1KMT2ALMNAKITPKM | |
| SCHEMBL27275299 | 0.74 | LMNA (0.49) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL27275411 | 0.74 | BRD4 (0.52) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL27275617 | 0.74 | MAPT (0.42) | MEN1KMT2ALMNAKITPKM | |
| SCHEMBL27275408 | 0.73 | MAPT (0.52) | MEN1KMT2AMAPTTP53THRB | |
| SCHEMBL27275409 | 0.73 | MEN1 (0.41) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL27275102 | 0.71 | LMNA (0.49) | MEN1KMT2ALMNAKITPKM | |
| SCHEMBL24876258 | 0.71 | LMNA (0.53) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL31679874 | 0.71 | LMNA (0.53) | MEN1KMT2ALMNAPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133220-A1 | INHIBITORS OF α-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2024-06-27 | — | — | WO | disclosed |