Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27275406 | 0.82 | LMNA (0.46) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL27275302 | 0.77 | MAPT (0.50) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL27275411 | 0.74 | BRD4 (0.52) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL27275299 | 0.74 | LMNA (0.49) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL27275408 | 0.73 | MAPT (0.52) | MEN1KMT2ATHRBSMN1; SMN2POLB | |
| SCHEMBL27275402 | 0.73 | MEN1 (0.43) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL27275617 | 0.69 | MAPT (0.42) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL27275212 | 0.69 | LMNA (0.49) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL30987773 | 0.67 | GRIN2D (0.46) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL27275076 | 0.67 | GRIN2D (0.46) | MEN1KMT2ALMNAPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133220-A1 | INHIBITORS OF α-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2024-06-27 | — | — | WO | disclosed |