Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876355 | 0.83 | MEN1 (0.63) | LMNAMAPTSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL27275409 | 0.82 | MEN1 (0.41) | LMNAMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL24876014 | 0.80 | MEN1 (0.62) | LMNAMAPTSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL27275302 | 0.79 | MAPT (0.50) | LMNAMAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL24876644 | 0.78 | MEN1 (0.66) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27275402 | 0.78 | MEN1 (0.43) | LMNAMAPTALDH1A1TP53MEN1 | |
| SCHEMBL27275411 | 0.77 | BRD4 (0.52) | LMNAMAPTSMN1; SMN2ATMMEN1 | |
| SCHEMBL27275299 | 0.77 | LMNA (0.49) | LMNAMAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL27275408 | 0.76 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1TP53ATM | |
| SCHEMBL31680056 | 0.73 | MEN1 (0.60) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133220-A1 | INHIBITORS OF α-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2024-06-27 | — | — | WO | disclosed |