Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27281075 | 0.89 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL27280283 | 0.84 | USP2 (0.32) | — | |
| SCHEMBL29152151 | 0.78 | MAOB (0.30) | — | |
| SCHEMBL27275776 | 0.76 | GAA (0.40) | — | |
| SCHEMBL27590550 | 0.74 | MAOB (0.33) | PGR | |
| SCHEMBL13456762 | 0.69 | PGR (0.40) | PGRAKR1B1 | |
| SCHEMBL27275777 | 0.68 | BRD4 (0.40) | — | |
| SCHEMBL10358498 | 0.67 | BRD4 (0.55) | PGRAKR1B1 | |
| SCHEMBL27279443 | 0.67 | MTNR1A (0.31) | — | |
| SCHEMBL27272118 | 0.67 | PARP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020098-C | Production for thiolactam-N-acetic acid derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-03-17 | — | — | CN | disclosed |
| CN-87102891-A | Production and use of sulfurized lactam-N-acetic acid derivatives | — | 1987-11-04 | — | — | CN | disclosed |