Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 13/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814972 | 0.99 | TRPM8 (0.50) | TRPM8TP53THRBPPARGPPARA | |
| SCHEMBL10419468 | 0.80 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL27277079 | 0.77 | CTRC (0.56) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL13418942 | 0.77 | PPARG (0.57) | TRPM8PPARGPPARAHPGDRAB9A | |
| SCHEMBL11576734 | 0.76 | CTRC (0.58) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL27274330 | 0.76 | PPARG (0.51) | TRPM8PPARGPPARANPC1RAB9A | |
| SCHEMBL9613979 | 0.76 | PPARG (0.63) | PPARGPPARAHPGD | |
| SCHEMBL20445991 | 0.76 | TRPM8 (0.53) | TRPM8TP53THRBPPARGPPARA | |
| SCHEMBL4257140 | 0.75 | PPARG (0.65) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL10420385 | 0.75 | PPARA (0.60) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1018548-B | CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-07 | — | — | CN | disclosed |
| CN-88100219-A | New carboxylic acid derivative and preparation technology thereof and the medicinal compositions that contains these derivatives | — | 1988-07-27 | — | — | CN | disclosed |