Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 13/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27276885 | 0.99 | TRPM8 (0.51) | TRPM8TP53THRBPPARGPPARA | |
| SCHEMBL10419468 | 0.81 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL11576734 | 0.78 | CTRC (0.58) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL9614187 | 0.77 | PPARG (0.55) | TP53PPARGPPARAHPGD | |
| SCHEMBL10420385 | 0.77 | PPARA (0.60) | PPARGPPARA | |
| SCHEMBL27277079 | 0.76 | CTRC (0.56) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL9814963 | 0.76 | PPARG (0.50) | TRPM8PPARGPPARANPC1RAB9A | |
| SCHEMBL9614177 | 0.76 | PPARG (0.61) | PPARGPPARAHPGD | |
| SCHEMBL9614241 | 0.76 | PPARG (0.50) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL10419185 | 0.76 | PPARA (0.78) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275024-B1 | CARBOXYLIC-ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |
| US-4833161-A | ANTIDIABETIC AGENTS, ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-23 | — | — | US | disclosed |
| EP-0275024-A1 | Carboxylic-acid derivatives, processes for their preparation and medicaments containing these compounds | Roche Diagnostics GmbH (DE) | 1988-07-20 | — | — | EP | disclosed |