SCHEMBL20445991

SCHEMBL20445991

Cc1ccc(OC(Cc2cccs2)C(N)=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TRPM8 Q7Z2W7 12/20 0.53
▸ TP53 P04637 1/20 0.50
▸ THRB P10828 1/20 0.50
▸ HPGD P15428 2/20 0.49
▸ RAB9A P51151 4/20 0.48
▸ CYP2C19 P33261 2/20 0.48
▸ NPC1 O15118 2/20 0.48
▸ CYP1A2 P05177 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ PPARG P37231 1/20 0.46
▸ PPARA Q07869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28194650 0.76 HPGD (0.59) TRPM8TP53THRBHPGDRAB9A
SCHEMBL27276885 0.76 TRPM8 (0.51) TRPM8TP53THRBHPGDRAB9A
SCHEMBL9814972 0.75 TRPM8 (0.50) TRPM8TP53THRBHPGDRAB9A
SCHEMBL28254369 0.74 HPGD (0.57) TRPM8TP53THRBHPGDRAB9A
SCHEMBL5758339 0.72 RAB9A (0.58) HPGDRAB9ACYP2C19NPC1
SCHEMBL28195169 0.72 HPGD (0.62) TRPM8TP53THRBHPGDRAB9A
SCHEMBL28254374 0.72 HPGD (0.55) TRPM8TP53THRBHPGDRAB9A
SCHEMBL6122797 0.72 CYP2C19 (0.61) HPGDRAB9ACYP2C19NPC1
SCHEMBL1905227 0.71 CYP2C19 (0.59) HPGDRAB9ACYP2C19NPC1
SCHEMBL2712722 0.71 CYP2C19 (0.59) RAB9ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11160894-B2 Perfume emanating device FIRMENICH SA (CH) 2021-11-02 — — US disclosed
US-20180264156-A1 PERFUME EMANATING DEVICE FIRMENICH SA (CH) 2018-09-20 — — US disclosed
EP-3355944-A1 PERFUME EMANATING DEVICE Firmenich SA (CH) 2018-08-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11160894-B2 Perfume emanating device DPM1, SURF4, FAAH2 TRPM8 151/4885TP53 3063/4885THRB 4444/4885
US-20180264156-A1 PERFUME EMANATING DEVICE DPM1, SURF4, FAAH2 TRPM8 151/4885TP53 3063/4885THRB 4444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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