Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432934 | 0.90 | RXRA (0.47) | KDM4ERXRARXRBLMNAALDH1A1 | |
| SCHEMBL27280517 | 0.86 | KDM4E (0.45) | KDM4ERXRARXRBLMNAALDH1A1 | |
| SCHEMBL9433895 | 0.83 | KDM4E (0.47) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9433007 | 0.82 | ICAM1 (0.53) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9432872 | 0.81 | KDM4E (0.59) | KDM4ERXFP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9433674 | 0.80 | ICAM1 (0.56) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9433069 | 0.79 | EDNRA (0.55) | MEN1KMT2APKM | |
| SCHEMBL9433742 | 0.79 | RXRA (0.43) | KDM4ERXFP1RXRARXRBLMNA | |
| SCHEMBL20535044 | 0.77 | KDM4E (0.61) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL6239909 | 0.75 | KDM4E (0.45) | KDM4ELMNAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |