Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432912 | 0.90 | EDNRA (0.60) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL9433069 | 0.88 | EDNRA (0.55) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL9434162 | 0.83 | CASP3 (0.58) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9433482 | 0.83 | KDM4E (0.64) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9432765 | 0.82 | EDNRA (0.50) | EDNRACASP3SENP8SENP7SENP6 | |
| SCHEMBL27280517 | 0.80 | KDM4E (0.45) | SMN1; SMN2MAPTKDM4EALDH1A1TP53 | |
| SCHEMBL9432926 | 0.78 | NPC1 (0.58) | L3MBTL1SMN1; SMN2MAPTPOLBKDM4E | |
| SCHEMBL18702641 | 0.77 | KDM4E (0.56) | EDNRAL3MBTL1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL29502927 | 0.77 | KDM4E (0.56) | EDNRAL3MBTL1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL720265 | 0.76 | CASP3 (0.60) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |