Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877258 | 0.87 | ALDH1A1 (0.44) | ALDH1A1ALOX15TSHRNR4A1NR4A2 | |
| SCHEMBL11329456 | 0.87 | ALDH1A1 (0.54) | ALDH1A1ALOX15TSHRNR4A1NR4A2 | |
| SCHEMBL5988902 | 0.86 | ALDH1A1 (0.55) | ALDH1A1ALOX15TSHRKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL28047976 | 0.84 | PRNP (0.45) | ALDH1A1ALOX15TSHRNR4A1NR4A2 | |
| SCHEMBL7477512 | 0.84 | CLCN2 (0.50) | ALDH1A1ALOX15TSHRKDM4EHPGD | |
| SCHEMBL8415183 | 0.82 | HNF4A (0.58) | ALDH1A1ALOX15SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL27930244 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ALOX15TSHRNR4A1NR4A2 | |
| SCHEMBL8578593 | 0.80 | ALDH1A1 (0.57) | ALDH1A1ALOX15TSHRNR4A1NR4A2 | |
| SCHEMBL8989403 | 0.80 | CLCN2 (0.50) | ALDH1A1ALOX15TSHRKDM4EHPGD | |
| SCHEMBL2292100 | 0.80 | TSHR (0.58) | ALDH1A1TSHRKDM4ECASP6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646171-A | 2-hydroxy-2-methyl-1-phenyl-1-propyl ketone synthesis process | 吕艳 | 2016-06-08 | — | — | CN | claimed |
| CN-100497314-C | Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them | AVENTIS PHARMA GMBH (DE) | 2009-06-10 | — | — | CN | claimed |
| CN-101208342-A | Pyrrolobenzodiazepine * pyridine carboxamides and derivatives as follicle stimulating hormone receptor antagonists | WYETH CORP (US) | 2008-06-25 | — | — | CN | claimed |
| CN-101171247-A | Pyrrole derivatives as DNA gyrase and topoisomerase inhibitors | ASTRAZENECA AB (SE) | 2008-04-30 | — | — | CN | claimed |
| CN-100364978-C | Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines | AVENTIS PHARMA GMBH (DE) | 2008-01-30 | — | — | CN | claimed |
| CN-100349856-C | Propionic acid derivatives and their use as hPPAR activators | SMITHKLINE BEECHAM CORP (US) | 2007-11-21 | — | — | CN | claimed |
| CN-1798737-A | Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines | AVENTIS PHARMA GMBH (DE) | 2006-07-05 | — | — | CN | claimed |
| CN-1675168-A | Propionic acid derivatives and their use as hPPARs activators | SMITHKLINE BEECHAM CORP (US) | 2005-09-28 | — | — | CN | claimed |
| CN-1617856-A | Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them | AVENTIS PHARMA GMBH (DE) | 2005-05-18 | — | — | CN | claimed |
| CN-1538827-A | Compositions and methods for making formable in vivo implants, and implants made thereby | — | 2004-10-20 | — | — | CN | claimed |
| CN-107667108-A | NAPHTHYRIDINE COMPOUNDS AS JAK KINASE INHIBITORS | 施万生物制药研发IP有限责任公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-107635558-A | Bu Luomo domain inhibitor | 赛尔基因昆蒂赛尔研究公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-104684533-B | Agent for changing the colour of keratin fibres, comprising an aliphatic substance and a rheology-modifying polymer in an emulsion system | 欧莱雅 | 2018-01-05 | — | — | CN | disclosed |
| CN-104334131-B | Ocular drug delivery device and application method | 杜克大学 | 2017-06-16 | — | — | CN | disclosed |
| CN-106536502-A | Phenyl tetrahydroisoquinoline compound substituted with heteroaryl | 大正制药株式会社 | 2017-03-22 | — | — | CN | disclosed |
| CN-1113872-C | Tricyclicbenzo [3] isoindole and benzo (h) isoquinoline | HOFFMANN LA ROCHE (CH) | 2003-07-09 | — | — | CN | disclosed |
| CN-1243510-A | Tricyclicbenzo [3] isoindole and benzo (h) isoquinoline | HOFFMANN LA ROCHE (CH) | 2000-02-02 | — | — | CN | disclosed |
| CN-1226817-A | Hair dye compositions and process | REVLON CONSUMER PROD CORP (US) | 1999-08-25 | — | — | CN | disclosed |
| CN-1010314-B | Novel platinum complex production method | NIPPON KAYAKU KK (JP) | 1990-11-07 | — | — | CN | disclosed |
| CN-86105441-A | Novel platinum complex production method | — | 1987-03-11 | — | — | CN | disclosed |