Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989403 | 0.89 | CLCN2 (0.50) | CLCN2MRGPRX4HMGB1GABRA1GABRB2 | |
| SCHEMBL7877258 | 0.89 | ALDH1A1 (0.44) | CLCN2MRGPRX4HMGB1FOLH1ALDH1A1 | |
| SCHEMBL578127 | 0.88 | CLCN2 (0.56) | CLCN2MRGPRX4HMGB1GABRA1GABRB2 | |
| Ammonia Solution, Strong SCHEMBL29557133 | 0.86 | CLCN2 (0.54) | CLCN2MRGPRX4HMGB1GABRA1GABRB2 | |
| SCHEMBL27280577 | 0.84 | ALDH1A1 (0.52) | HMGB1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL15344588 | 0.81 | CLCN2 (0.50) | CLCN2HMGB1GABRA1GABRB2FOLH1 | |
| SCHEMBL200521 | 0.81 | CLCN2 (0.50) | CLCN2MRGPRX4HMGB1GABRA1GABRB2 | |
| SCHEMBL1355391 | 0.80 | ALDH1A1 (0.52) | CLCN2MRGPRX4HMGB1ALDH1A1ALOX15 | |
| SCHEMBL607739 | 0.80 | GABRA1 (0.50) | GABRA1GABRB2ALDH1A1TSHRHTT | |
| SCHEMBL5988902 | 0.79 | ALDH1A1 (0.55) | ALDH1A1ALOX15TSHRHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |
| EP-0409027-A1 | Indole derivatives, process for their preparation and their use in pharmaceuticals | BAYER AG (DE) | 1991-01-23 | — | — | EP | disclosed |