Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477512 | 0.89 | CLCN2 (0.50) | ALDH1A1HMGB1ALOX15FOLH1TSHR | |
| SCHEMBL8989403 | 0.89 | CLCN2 (0.50) | ALDH1A1HMGB1ALOX15FOLH1TSHR | |
| SCHEMBL27280577 | 0.87 | ALDH1A1 (0.52) | ALDH1A1HMGB1ALOX15FOLH1TSHR | |
| SCHEMBL6050041 | 0.82 | L3MBTL1 (0.50) | ALDH1A1TSHRNR4A1MAPT | |
| SCHEMBL29421029 | 0.82 | L3MBTL1 (0.50) | ALDH1A1TSHRNR4A1MAPT | |
| SCHEMBL28703712 | 0.81 | BID (0.43) | HMGB1FOLH1TSHRCLCN2HTT | |
| SCHEMBL602386 | 0.81 | FOLH1 (0.59) | ALDH1A1HMGB1ALOX15FOLH1TSHR | |
| SCHEMBL3291708 | 0.80 | HMGB1 (0.62) | ALDH1A1HMGB1ALOX15FOLH1TSHR | |
| SCHEMBL11329456 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HMGB1ALOX15TSHRNR4A1 | |
| SCHEMBL28148009 | 0.80 | FOLH1 (0.47) | ALDH1A1HMGB1ALOX15FOLH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699525-A | Method for preparing 2,3-dichlorobenzaldehyde through continuous oxidization of 2,3-dichlorotoluene | 常州大学 | 2017-05-24 | — | — | CN | disclosed |
| US-6326509-B1 | REACTING THE CORRESPONDING ACID CHLORIDE WITH TIN CHLORIDE AND 1,3,5-TRIOXANE | BRISTOL-MYERS SQUIBB COMPANY | 2001-12-04 | — | — | US | disclosed |