Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27284528 | 0.82 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL27277486 | 0.79 | HTR2A (0.47) | SLC6A3 | |
| SCHEMBL19749365 | 0.72 | SLC6A2 (0.46) | SLC6A3SLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL7366491 | 0.72 | SLC6A2 (0.45) | SLC6A3SLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL14300482 | 0.70 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3951825 | 0.70 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL764313 | 0.69 | SLC6A2 (0.49) | SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL4879272 | 0.69 | SLC6A2 (0.49) | SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL9580445 | 0.69 | SLC6A2 (0.49) | SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL9580447 | 0.69 | SLC6A2 (0.49) | SLC6A3SLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1012733-B | Process for the preparation of therapeutic agents | BOOTS CO PLC (GB) | 1991-06-05 | — | — | CN | disclosed |
| CN-86100954-A | The preparation method of therapeutical agent and application | — | 1986-09-03 | — | — | CN | disclosed |