Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839488 | 0.83 | SLC6A3 (0.47) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL9839481 | 0.83 | SLC6A3 (0.47) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL4000922 | 0.77 | MDM2 (0.43) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL28202984 | 0.72 | SLC6A3 (0.49) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL27281137 | 0.72 | SLC6A3 (0.41) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL27284528 | 0.72 | SLC6A3 (0.45) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL9870878 | 0.72 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4CYP2D6KCNH2 | |
| SCHEMBL8146309 | 0.71 | KDM1A (0.48) | SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL7004269 | 0.71 | KDM1A (0.48) | SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL7004268 | 0.71 | KDM1A (0.48) | SLC6A2SLC6A3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715620-B1 | 1-ARYLCYCLOALKYL SULPHIDES, SULPHOXIDES AND SULPHONES FOR THE TREATMENT OF DEPRESSION, ANXIETY AND PARKINSON'S DISEASE | KNOLL AG (DE) | 1998-10-28 | — | — | EP | disclosed |
| EP-0715620-A1 | 1-ARYLCYCLOALKYL SULPHIDES, SULPHOXIDES AND SULPHONES FOR THE TREATMENT OF DEPRESSION, ANXIETY AND PARKINSON'S DISEASE | Knoll AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| WO-1994026704-A1 | 1-ARYLCYCLOALKYL SULPHIDES, SULPHOXIDES AND SULPHONES FOR THE TREATMENT OF DEPRESSION, ANXIETY AND PARKINSON'S DISEASE | THE BOOTS COMPANY PLC (GB) | 1994-11-24 | — | — | WO | disclosed |