SCHEMBL2728344

SCHEMBL2728344

Fc1ccc2nsnc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 3/20 0.54
MAPT P10636 7/20 0.50
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
KMT2A Q03164 6/20 0.47
TXNRD1 Q16881 1/20 0.45
TXNRD3 Q86VQ6 1/20 0.45
TXNRD2 Q9NNW7 1/20 0.45
KDM4E B2RXH2 4/20 0.43
GFER P55789 2/20 0.41
AXL P30530 1/20 0.41
TSHR P16473 1/20 0.40
PTPN1 P18031 1/20 0.39
BACE1 P56817 1/20 0.39
ALDH1A1 P00352 5/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
MEN1 O00255 5/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTT P42858 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL28555624 0.88 PTPN11 (0.44) PTPN11MAPTNPC1RAB9AKMT2A
SCHEMBL23244621 0.86 PTPN11 (0.42) PTPN11MAPTNPC1RAB9AKMT2A
SCHEMBL3858998 0.74 PTPN11 (0.58) PTPN11MAPTNPC1RAB9AKMT2A
SCHEMBL6322293 0.73 GRM5 (0.48) PTPN11PTPN1
SCHEMBL2726241 0.73 PTPN11 (0.44) PTPN11MAPTNPC1RAB9AKMT2A
SCHEMBL19707 0.70 PTPN11 (0.54) PTPN11MAPTNPC1RAB9AKMT2A
SCHEMBL18500595 0.70 PTPN11 (0.54) PTPN11MAPTNPC1RAB9AKMT2A
SCHEMBL2729225 0.70 PTPN11 (0.54) PTPN11MAPTNPC1RAB9AKMT2A
SCHEMBL4830150 0.70 PTPN11 (0.54) PTPN11MAPTNPC1RAB9AKMT2A
SCHEMBL922408 0.70 PTPN11 (1.00) PTPN11MAPTNPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12527146-B2 Sputter protective layer for organic electronic devices SMARTKEM LIMITED (GB) 2026-01-13 US claimed
CN-112352326-B Sputter protection layer for organic electronic devices 斯马特凯姆有限公司 2025-05-23 CN claimed
CN-112500557-B Asymmetric donor-acceptor-donor electrochromic polymer based on 5-fluoro-2, 1, 3-benzothiadiazole and application thereof 电子科技大学中山学院 2023-08-04 CN claimed
CN-114203908-A Optically transparent nonvolatile transistor memory and preparation method thereof 吉林大学 2022-03-18 CN claimed
CN-112500557-A Asymmetric donor-acceptor-donor electrochromic polymer based on 5-fluoro-2, 1, 3-benzothiadiazole and application thereof 电子科技大学中山学院 2021-03-16 CN claimed
US-12527146-B2 Sputter protective layer for organic electronic devices SMARTKEM LIMITED (GB) 2026-01-13 US disclosed
WO-2025133616-A1 CONJUGATED POLYMER NANOPARTICLE BIOSENSORS STREAM BIO LTD (GB) 2025-06-26 WO disclosed
CN-112352326-B Sputter protection layer for organic electronic devices 斯马特凯姆有限公司 2025-05-23 CN disclosed
EP-4551637-A1 POLYMER SOLAR CELLS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2025-05-14 EP disclosed
EP-3815157-B1 SPUTTER PROTECTIVE LAYER FOR ORGANIC ELECTRONIC DEVICES SMARTKEM LTD (GB) 2024-10-16 EP disclosed
US-12075697-B2 Inert solution-processable molecular chromophores for organic electronic devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-27 US disclosed
US-12075697-B2 Inert solution-processable molecular chromophores for organic electronic devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-27 US disclosed
US-20130200354-A1 Conjugated Polymers and Their Use in Optoelectronic Devices POLYERA CORPORATION (US) 2013-08-08 US disclosed
US-20130200354-A1 Conjugated Polymers and Their Use in Optoelectronic Devices POLYERA CORPORATION (US) 2013-08-08 US disclosed
US-20130200355-A1 Conjugated Polymers and Their Use in Optoelectronic Devices POLYERA CORPORATION (US) 2013-08-08 US disclosed
US-20130200354-A1 Conjugated Polymers and Their Use in Optoelectronic Devices POLYERA CORPORATION (US) 2013-08-08 US disclosed
US-20130026459-A1 POLYMER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-31 US disclosed
US-20130026459-A1 POLYMER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-31 US disclosed
WO-2012054910-A1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES POLYERA CORPORTION (US) 2012-04-26 WO disclosed
WO-2012054910-A1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES POLYERA CORPORTION (US) 2012-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026459-A1 POLYMER COMPOUND SCO2, RER1, CRY1 PTPN11 1466/4885MAPT 2891/4885NPC1 3825/4885
US-12075697-B2 Inert solution-processable molecular chromophores for organic electronic devices KMO, TDO2, HTR3D PTPN11 3407/4885MAPT 600/4885NPC1 4139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.