Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052503 | 0.81 | ESR1 (0.61) | ESR1POLB | |
| SCHEMBL2728564 | 0.81 | GAA (0.69) | ESR1GAASMN1; SMN2POLBHTT | |
| SCHEMBL2252773 | 0.74 | TTBK1 (0.66) | — | |
| Sulfadoxine SCHEMBL41069 | 0.74 | ESR1 (1.00) | ESR1SMN1; SMN2DHFRTSHRCYP19A1 | |
| Sulfadoxine SCHEMBL29390814 | 0.74 | ESR1 (1.00) | ESR1SMN1; SMN2DHFRTSHRCYP19A1 | |
| Sulfadoxine SCHEMBL28537335 | 0.73 | ESR1 (0.97) | ESR1SMN1; SMN2DHFRTSHRCYP19A1 | |
| Sulfadoxine SCHEMBL27856131 | 0.73 | ESR1 (0.97) | ESR1SMN1; SMN2DHFRTSHRCYP19A1 | |
| Sulfadoxine SCHEMBL28436237 | 0.73 | ESR1 (0.97) | ESR1SMN1; SMN2DHFRTSHRCYP19A1 | |
| Sulfadoxine SCHEMBL28359083 | 0.73 | ESR1 (0.97) | ESR1SMN1; SMN2DHFRTSHRCYP19A1 | |
| SCHEMBL2256007 | 0.71 | LMNA (0.72) | POLBHTTALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236002-B2 | Pharmaceutical composition comprising a medicament and a water-swellable polymer | MALLINCKRODT VETERINARY INC (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0416722-B1 | Pharmaceutical compositions having differential drug release rate | PITMAN MOORE LTD (GB) | 1994-09-28 | — | — | EP | disclosed |
| US-5190760-A | Drugs for bactericides and anthelmintics | COOPERS ANIMAL HEALTH LIMITED (GB) | 1993-03-02 | — | — | US | disclosed |
| EP-0416722-A2 | Pharmaceutical compositions having differential drug release rate | PITMAN-MOORE LIMITED (GB) | 1991-03-13 | — | — | EP | disclosed |
| EP-0236002-A2 | Pharmaceutical composition comprising a medicament and a water-swellable polymer | MALLINCKRODT VETERINARY, INC. (US) | 1987-09-09 | — | — | EP | disclosed |