Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27285877 | 0.76 | MEN1 (0.43) | MAPK1TDP1MAPTNPSR1L3MBTL1 | |
| SCHEMBL6652948 | 0.75 | CES2 (0.50) | TDP1L3MBTL1CES2CES1PRMT1 | |
| SCHEMBL3259340 | 0.75 | CES2 (0.41) | MAPK1CES2CES1PRMT1ALDH1A1 | |
| SCHEMBL5691005 | 0.73 | CES2 (0.40) | MAPTNPSR1CES2CES1PRMT1 | |
| SCHEMBL10629688 | 0.73 | CES2 (0.44) | MAPK1CES2CES1PRMT1ALDH1A1 | |
| SCHEMBL28133289 | 0.70 | ALDH1A1 (0.39) | TDP1MAPTL3MBTL1CES2CES1 | |
| SCHEMBL5918159 | 0.70 | MEN1 (0.42) | MAPTNPSR1ALDH1A1GAACYP2C19 | |
| SCHEMBL8777365 | 0.68 | LMNA (0.52) | MAPK1TDP1L3MBTL1CES2CES1 | |
| SCHEMBL851397 | 0.68 | LMNA (0.52) | MAPK1TDP1L3MBTL1CES2CES1 | |
| SCHEMBL8777383 | 0.68 | LMNA (0.52) | MAPK1TDP1L3MBTL1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009102437-A | 2-HYDROXYACETOPHENONE OXIME DERIVATIVE | BAYER AG | 2009-05-14 | — | — | JP | disclosed |
| CN-1179956-C | Intermediate for preparing substituted dioxazine | — | 2004-12-15 | — | — | CN | disclosed |
| EP-0846691-B1 | Process for preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER CROPSCIENCE AG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6437153-B1 | O-HYDROXYETHYL-O'-ALKYLBENZOFURANDIONE DIOXIMES REARRANGED IN THE PRESENCE OF A DILENT, AN ACID OR A BASE; FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
| US-20020049319-A1 | O-hydroxyethyl-o'-alkylbenzofurandione dioximes rearranged in the presence of a dilent, an acid or a base; fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-04-25 | — | — | US | disclosed |
| CN-1082955-C | Process for preparing 3- (1-hydroxyphenyl-1-alkoxyiminomethyl) dioxazines | BAYER AG (DE) | 2002-04-17 | — | — | CN | disclosed |
| US-6335454-B1 | FUNGICIDE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| CN-1313283-A | Intermediate for preparing substituted dioxazine | BAYER AG (DE) | 2001-09-19 | — | — | CN | disclosed |
| US-6093837-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-25 | — | — | US | disclosed |
| US-6005104-A | INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES; PREPARED BY REARRANGING O-HYDROXYETHYL-O'-ALKYL-BENZOFURANDIONE DIOXIMES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| CN-1184811-A | Process for preparing 3- (1-hydroxyphenyl-1-alkoxyiminomethyl) dioxazines | BAYER AG (DE) | 1998-06-17 | — | — | CN | disclosed |
| EP-0846691-A1 | Process for preparation of 3-(1-hydroxyphenyl-1-alkoximinomethyl)dioxazines | BAYER AG (DE) | 1998-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049319-A1 | O-hydroxyethyl-o'-alkylbenzofurandione dioximes rearranged in the presence of a dilent, an acid or a base; fungicides | DDT, CYP4Z1, CYP51A1 | MAPK1 2165/4885TDP1 546/4885MAPT 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.