SCHEMBL27287166

SCHEMBL27287166

CC(C)(C)OC(=O)C1OCCS1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPK1 P28482 1/20 0.33
RECQL P46063 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30
HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4898716 0.78
SCHEMBL27743690 0.77 MAPK1 (0.31) MAPK1
SCHEMBL16940488 0.71 MAPK1 (0.37) USP2SMN1; SMN2MAPK1HRH3
SCHEMBL7870788 0.69 MAPK1 (0.38) USP2SMN1; SMN2MAPK1RECQLHRH3
SCHEMBL7870784 0.69 MAPK1 (0.38) USP2SMN1; SMN2MAPK1RECQLHRH3
SCHEMBL12192736 0.68 FAAH (0.35) MAPK1HRH3
SCHEMBL5789732 0.68
SCHEMBL9540306 0.68
SCHEMBL8806943 0.66 TSHR (0.36)
SCHEMBL8807082 0.66 TSHR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1109030-C Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides IAF BIOCHEM INT (CA) 2003-05-21 CN disclosed
CN-1097049-C Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides IAF BIOCHEM INT (CA) 2002-12-25 CN disclosed
CN-1083450-C Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides IAF BIOCHEM INT (CA) 2002-04-24 CN disclosed
CN-1050603-C Process for the preparation of intermediates used in a process for the diastereoselective synthesis of nucleosides IAF BIOCHEM INT (CA) 2000-03-22 CN disclosed
CN-1229078-A Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides IAF BIOCHEM INT (CA) 1999-09-22 CN disclosed
CN-1229079-A Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides IAF BIOCHEM INT (CA) 1999-09-22 CN disclosed
CN-1229080-A Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides IAF BIOCHEM INT (CA) 1999-09-22 CN disclosed
CN-1038591-C Process for diastereoselective synthesis of nucleosides IAF BIOCHEM INT (CA) 1998-06-03 CN disclosed
CN-1116204-A Process for diastereoselective synthesis of nucleosides IAF BIOCHEM INT (CA) 1996-02-07 CN disclosed
CN-1067654-A Process for diastereoselective synthesis of nucleosides IAF BIOCHEM INT (CA) 1993-01-06 CN disclosed