Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 10/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15179166 | 0.83 | CTSB (0.48) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL13827709 | 0.83 | MEN1 (0.59) | POLBCTSSCTSKALDH1A1MEN1 | |
| SCHEMBL19042806 | 0.83 | MEN1 (0.59) | POLBCTSSCTSKALDH1A1MEN1 | |
| SCHEMBL26178948 | 0.76 | MME (0.57) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL4725412 | 0.76 | MDM2 (0.50) | CTSBPOLBCTSLCTSSALDH1A1 | |
| SCHEMBL27270915 | 0.76 | MME (0.50) | MEN1KMT2ATAAR1 | |
| SCHEMBL14432427 | 0.76 | POLB (0.53) | CTSBPOLBCTSLCTSSCTSK | |
| SCHEMBL13154997 | 0.75 | FDPS (0.47) | KDM4EKMT2A | |
| SCHEMBL12524788 | 0.75 | ESR1 (0.51) | KDM4EMEN1KMT2ATAAR1 | |
| SCHEMBL9828630 | 0.75 | TACR1 (0.58) | CTSBPOLBCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |