Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | CPT1A | P50416 | 7/20 | 0.33 |
| ▸ | CPT2 | P23786 | 5/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726646 | 0.93 | NAPEPLD (0.34) | ROCK2CPT1ACPT2NOS1NOS2 | |
| SCHEMBL2726650 | 0.93 | NAPEPLD (0.34) | ROCK2CPT1ACPT2NOS1NOS2 | |
| Fumaric Acid SCHEMBL2733545 | 0.90 | NAPEPLD (0.33) | ROCK2CPT1ACPT2NOS1NOS2 | |
| SCHEMBL2728147 | 0.90 | SMN1; SMN2 (0.34) | ROCK2CPT1ACPT2NOS1NOS2 | |
| SCHEMBL6467759 | 0.88 | SMN1; SMN2 (0.34) | ROCK2CPT1ACPT2NOS1NOS2 | |
| SCHEMBL2727730 | 0.88 | CPT1A (0.34) | CPT1ACPT2TRPV1CPT1BSMN1; SMN2 | |
| SCHEMBL2727049 | 0.87 | CPT1A (0.35) | CPT1ACPT2TRPV1CPT1BSMN1; SMN2 | |
| SCHEMBL2729068 | 0.87 | CPT1A (0.36) | CPT1ACPT2CPT1BHCRTR1HCRTR2 | |
| SCHEMBL2729471 | 0.86 | SCD5 (0.34) | ROCK2CPT1ACPT2TRPV1CPT1B | |
| SCHEMBL2726586 | 0.85 | CPT1A (0.35) | CPT1ACPT2TRPV1CPT1BHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |