Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | NPR3 | P17342 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567141 | 0.83 | HSD11B1 (0.44) | MMP13HSD11B1MMP1MMP2MMP3 | |
| SCHEMBL27608526 | 0.81 | AAK1 (0.40) | AAK1ATML3MBTL1ALDH1A1RECQL | |
| SCHEMBL27535107 | 0.76 | SLC7A5 (0.40) | AAK1ATML3MBTL1ALDH1A1RECQL | |
| SCHEMBL28386851 | 0.76 | AAK1 (0.39) | AAK1ATML3MBTL1ALDH1A1RECQL | |
| SCHEMBL29488418 | 0.76 | AAK1 (0.39) | AAK1ATML3MBTL1ALDH1A1RECQL | |
| SCHEMBL23012998 | 0.76 | SLC7A5 (0.40) | AAK1ATML3MBTL1ALDH1A1RECQL | |
| SCHEMBL28386849 | 0.76 | AAK1 (0.39) | AAK1ATML3MBTL1ALDH1A1RECQL | |
| SCHEMBL27289804 | 0.74 | ITGA4 (0.41) | MMP13HSD11B1ATMALDH1A1 | |
| SCHEMBL7567145 | 0.74 | LTA4H (0.46) | MMP13HSD11B1MMP1AAK1L3MBTL1 | |
| SCHEMBL27764532 | 0.73 | MMP13 (0.42) | MMP13HSD11B1MMP1MMP2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039596-A | Preparation method in conjunction with the peptide of retroviral Protease | SMITHKLINE BECKMAN CORP (US) | 1990-02-14 | — | — | CN | disclosed |