Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16980439 | 0.98 | DPP4 (0.41) | DPP4OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL20756988 | 0.94 | OPRL1 (0.38) | DPP4OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL18664010 | 0.94 | OPRL1 (0.38) | DPP4OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL25489339 | 0.90 | SIGMAR1 (0.36) | DPP4OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL24494860 | 0.90 | SIGMAR1 (0.36) | DPP4OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL20756242 | 0.89 | OPRL1 (0.40) | DPP4OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL14519149 | 0.88 | ALDH1A1 (0.36) | DPP4OPRM1OPRL1OPRK1SIGMAR1 | |
| SCHEMBL14519158 | 0.88 | MEN1 (0.38) | DPP4OPRM1OPRL1OPRK1SIGMAR1 | |
| SCHEMBL22874788 | 0.87 | OPRM1 (0.49) | DPP4OPRM1OPRL1OPRK1CHRM2 | |
| SCHEMBL20756943 | 0.86 | MEN1 (0.37) | DPP4OPRM1OPRL1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129763-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2023247595-A1 | PYRAZOLOPYRAZINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |