Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | QPCT | Q16769 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034505 | 0.86 | CRHBP (0.70) | CRHBPCRHR2QPCTALDH1A1HTT | |
| SCHEMBL9530573 | 0.86 | QPCT (0.54) | CRHBPCRHR2QPCTIDO1ALDH1A1 | |
| SCHEMBL27182530 | 0.84 | EEF2K (0.56) | IDO1ALDH1A1MAPTROCK1MYLK4 | |
| SCHEMBL27291650 | 0.83 | CRHBP (0.62) | CRHBPCRHR2QPCTALDH1A1MAPT | |
| SCHEMBL27290775 | 0.83 | CRHBP (0.62) | CRHBPCRHR2QPCTALDH1A1HTT | |
| SCHEMBL28034521 | 0.81 | CRHBP (0.64) | CRHBPCRHR2QPCTALDH1A1MAPT | |
| SCHEMBL9529977 | 0.81 | MAPT (0.58) | IDO1ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL27290720 | 0.80 | MAPT (0.60) | CRHBPCRHR2QPCTALDH1A1MAPT | |
| SCHEMBL6520812 | 0.79 | HTT (0.60) | CRHBPCRHR2QPCTALDH1A1HTT | |
| SCHEMBL27290748 | 0.78 | ALDH1A1 (0.59) | CRHBPCRHR2QPCTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049236-A1 | CHIRAL GAMMA LACTAM DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PREPARATION METHOD THEREFOR | 고려대학교 산학협력단 | 2024-03-07 | — | — | WO | disclosed |