Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 4/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295850 | 0.82 | ALDH1A1 (0.72) | MAPTALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL27107264 | 0.82 | IDO1 (0.52) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9530573 | 0.82 | QPCT (0.54) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL27146381 | 0.82 | IDO1 (0.52) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL27146380 | 0.82 | IDO1 (0.52) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL18737570 | 0.82 | FNTA (0.43) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL27290761 | 0.81 | CRHBP (0.56) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL27182530 | 0.80 | EEF2K (0.56) | MAPTALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL5449567 | 0.78 | IDO1 (0.78) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL22831500 | 0.77 | IDO1 (0.47) | MAPTALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907766-B2 | Sweetness receptor antagonist | AJINOMOTO CO., INC. (JP) | 2018-03-06 | — | — | US | claimed |
| EP-3162366-A1 | SWEETNESS RECEPTOR ANTAGONIST | Ajinomoto Co., Inc. (JP) | 2017-05-03 | — | — | EP | claimed |
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | AJINOMOTO CO., INC. (JP) | 2017-04-13 | — | — | US | claimed |
| US-9907766-B2 | Sweetness receptor antagonist | AJINOMOTO CO., INC. (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9907766-B2 | Sweetness receptor antagonist | AJINOMOTO CO., INC. (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9907766-B2 | Sweetness receptor antagonist | AJINOMOTO CO., INC. (JP) | 2018-03-06 | — | — | US | disclosed |
| EP-3162366-A1 | SWEETNESS RECEPTOR ANTAGONIST | Ajinomoto Co., Inc. (JP) | 2017-05-03 | — | — | EP | disclosed |
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | AJINOMOTO CO., INC. (JP) | 2017-04-13 | — | — | US | disclosed |
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | AJINOMOTO CO., INC. (JP) | 2017-04-13 | — | — | US | disclosed |
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | AJINOMOTO CO., INC. (JP) | 2017-04-13 | — | — | US | disclosed |
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | GPR119, GLP1R, SUCNR1 | MAPT 4748/4885ALDH1A1 1889/4885HTT 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.