Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27290761 | 0.86 | CRHBP (0.56) | QPCTIDO1MEN1KMT2AMAPT | |
| SCHEMBL27182530 | 0.85 | EEF2K (0.56) | IDO1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9529977 | 0.82 | MAPT (0.58) | IDO1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22831502 | 0.82 | IDO1 (0.47) | QPCTIDO1MEN1KMT2AMAPT | |
| SCHEMBL22831500 | 0.82 | IDO1 (0.47) | QPCTIDO1MEN1KMT2AMAPT | |
| SCHEMBL6295850 | 0.76 | ALDH1A1 (0.72) | IDO1NPC1MEN1KMT2AMAPT | |
| SCHEMBL27107264 | 0.76 | IDO1 (0.52) | IDO1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27146380 | 0.76 | IDO1 (0.52) | IDO1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27146381 | 0.76 | IDO1 (0.52) | IDO1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL26485884 | 0.75 | MAPT (0.61) | QPCTNPC1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |