Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607140 | 0.92 | TDP1 (0.43) | CYP4F2CYP4A11APOBEC3GPOLBKDM4E | |
| SCHEMBL29681348 | 0.92 | TDP1 (0.43) | CYP4F2CYP4A11APOBEC3GPOLBKDM4E | |
| SCHEMBL29681353 | 0.92 | TDP1 (0.43) | CYP4F2CYP4A11APOBEC3GPOLBKDM4E | |
| 1,6-Hexanediol SCHEMBL28386159 | 0.84 | APOBEC3G (0.48) | CYP4F2CYP4A11APOBEC3GPOLBKDM4E | |
| SCHEMBL9672220 | 0.84 | LIPG (0.43) | CYP4F2CYP4A11APOBEC3GPOLBKDM4E | |
| SCHEMBL30563551 | 0.84 | APOBEC3G (0.48) | CYP4F2CYP4A11APOBEC3GMPOTDP1 | |
| SCHEMBL30750761 | 0.84 | LIPG (0.43) | CYP4F2CYP4A11APOBEC3GPOLBKDM4E | |
| SCHEMBL27891 | 0.84 | APOBEC3G (0.48) | CYP4F2CYP4A11APOBEC3GMPOTDP1 | |
| SCHEMBL169275 | 0.83 | TAAR1 (0.58) | KDM4EMPOSLC6A4TAAR1MGLL | |
| SCHEMBL2178352 | 0.82 | LIPG (0.47) | CYP4F2CYP4A11APOBEC3GPOLBMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336717-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| US-10336717-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| EP-2754638-B1 | FILM-FORMING MATERIAL, GROUP IV METAL OXIDE FILM AND VINYLENE DIAMIDE COMPLEX | TOSOH CORP (JP) | 2018-11-07 | — | — | EP | disclosed |
| CN-105001254-B | The manufacturing method of film material, IV family metal oxide films | 东曹株式会社 | 2018-09-11 | — | — | CN | disclosed |
| US-20180110824-A1 | Macrocyclic Modulators of the Ghrelin Receptor | OCERA THERAPEUTICS, INC. | 2018-04-26 | — | — | US | disclosed |
| US-20180110824-A1 | Macrocyclic Modulators of the Ghrelin Receptor | OCERA THERAPEUTICS, INC. | 2018-04-26 | — | — | US | disclosed |
| EP-2939996-B1 | GROUP 5 METAL OXO-ALKOXO COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR MANUFACTURING GROUP 5 METAL OXIDE FILM | TOSOH CORP (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-2339594-B1 | COMPOSITION FOR PRODUCING METAL FILM, METHOD FOR PRODUCING METAL FILM, AND METHOD FOR PRODUCING METAL POWDER | TOSOH CORP (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-2457893-B1 | Intermediates for macrocyclic modulators of the ghrelin receptor | OCERA THERAPEUTICS INC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-9663541-B2 | Group 5 metal oxo-alkoxo complex, method for producing same, and method for manufacturing group 5 metal oxide film | TOSOH CORPORATION (JP) | 2017-05-30 | — | — | US | disclosed |
| US-20070021331-A1 | Methods of using macrocyclic modulators of the ghrelin receptor | TRANZYME PHARMA INC. | 2007-01-25 | — | — | US | disclosed |
| US-20070021331-A1 | Methods of using macrocyclic modulators of the ghrelin receptor | TRANZYME PHARMA INC. | 2007-01-25 | — | — | US | disclosed |
| EP-1689712-A1 | 4-PHENYLPIPERIDINE DERIVATIVES AS RENIN INHIBITORS | Novartis AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| CN-1748012-A | Adhesive tape for sticking wafer | FURUKAWA ELECTRIC CO LTD (JP) | 2006-03-15 | — | — | CN | disclosed |
| WO-2006009645-A1 | METHODS OF USING MACROCYCLIC MODULATORS OF THE GHRELIN RECEPTOR | TRANZYME PHARMA, INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| CN-1661790-A | Particle removing member of substrate processing equipment | NITTO DENKO CORP (JP) | 2005-08-31 | — | — | CN | disclosed |
| WO-2005051911-A1 | 4-PHENYLPIPERIDINE DERIVATIVES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2005-06-09 | — | — | WO | disclosed |
| US-4517327-A | AMINO RESIN, STYRENE-(METH)ALLYL ALCOHOL COMPOLYER, ACRYLIC OR POLYESTER RESIN | MONSANTO COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| US-4031290-A | ALPHA-BETA MONOMERS, CATALYSIS | PPG INDUSTRIES, INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4016332-A | OF ETHYLENICALLY UNSATURATED MONOMERS | PPG INDUSTRIES, INC. (US) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110824-A1 | Macrocyclic Modulators of the Ghrelin Receptor | GHSR, GIPR, GHRHR | CYP4F2 3092/4885CYP4A11 877/4885APOBEC3G 4872/4885 |
| US-10336717-B2 | Inhibitors of beta-secretase | BACE1, BACE2, PSEN1 | CYP4F2 3082/4885CYP4A11 1014/4885APOBEC3G 2971/4885 |
| US-20070021331-A1 | Methods of using macrocyclic modulators of the ghrelin receptor | GHSR, GHRHR, GIPR | CYP4F2 2948/4885CYP4A11 896/4885APOBEC3G 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.