Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.58 |
| ▸ | CTSD | P07339 | 4/20 | 0.56 |
| ▸ | REN | P00797 | 5/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332668 | 0.92 | ACE (0.68) | ACECTSDRENKLK5PSEN1 | |
| SCHEMBL7326125 | 0.89 | ACE (0.66) | ACECTSDRENKLK5 | |
| SCHEMBL10377248 | 0.82 | ACE (0.65) | ACERENBCL2PSMB10PSMB2 | |
| SCHEMBL7332128 | 0.82 | ACE (0.65) | ACERENBCL2PSMB10PSMB2 | |
| SCHEMBL6161729 | 0.81 | BCL2 (0.64) | RENKLK5BCL2PTPN1YAP1 | |
| SCHEMBL3350988 | 0.81 | BCL2 (0.64) | RENKLK5BCL2PTPN1YAP1 | |
| SCHEMBL3500186 | 0.81 | BCL2 (0.64) | RENKLK5BCL2PTPN1YAP1 | |
| SCHEMBL28961339 | 0.80 | CTSD (0.67) | CTSDRENKLK5PSEN1PSEN2 | |
| SCHEMBL11661865 | 0.80 | CTSD (0.67) | CTSDRENKLK5PSEN1PSEN2 | |
| SCHEMBL12706388 | 0.80 | BCL2 (0.64) | RENBCL2PSMB1PSMB8PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039596-A | Preparation method in conjunction with the peptide of retroviral Protease | SMITHKLINE BECKMAN CORP (US) | 1990-02-14 | — | — | CN | disclosed |