Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729483 | 1.00 | BCHE (0.38) | BCHEACHEHASPINLIMK1MAOA | |
| SCHEMBL2729487 | 0.87 | BCHE (0.41) | BCHEACHEHASPIN | |
| SCHEMBL2719938 | 0.82 | LIMK1 (0.52) | LIMK1DYRK1A | |
| SCHEMBL15312161 | 0.76 | BCHE (0.44) | BCHEACHEHASPINMAOADYRK1A | |
| SCHEMBL2720296 | 0.75 | ALKBH5 (0.49) | BCHEACHEHASPINLIMK1MAOA | |
| SCHEMBL2733460 | 0.74 | HASPIN (0.44) | BCHEACHEHASPINDYRK1A | |
| SCHEMBL28928549 | 0.70 | ACHE (0.60) | BCHEACHEHASPINLIMK1MAOA | |
| SCHEMBL21814269 | 0.63 | BRD4 (0.40) | BCHEACHELIMK1 | |
| SCHEMBL17030436 | 0.63 | HSD17B10 (0.46) | LIMK1 | |
| SCHEMBL18160217 | 0.63 | ALKBH5 (0.65) | LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635575-A1 | CARBAZOLE AND CARBOLINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC APPLICATIONS THEREOF | Philip Morris Products S.a.s. (CH) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059232-A1 | CARBAZOLE AND CARBOLINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC APPLICATIONS THEREOF | PHILIP MORRIS PRODUCTS S.A (CH) | 2012-05-10 | — | — | WO | disclosed |