Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8188456 | 0.81 | GRIN2B (0.44) | DRD3DRD2PSEN1PSEN2APH1B | |
| SCHEMBL9716394 | 0.79 | HRH3 (0.41) | DRD3DRD2DRD4SLC6A2SLC6A4 | |
| SCHEMBL12125958 | 0.79 | DRD3 (0.57) | DRD3DRD2DRD4CHRM1ADRA2C | |
| SCHEMBL9769473 | 0.77 | SIGMAR1 (0.43) | DRD3DRD2DRD4GRIN2BSIGMAR1 | |
| SCHEMBL3467135 | 0.76 | DRD2 (0.43) | DRD3DRD2DRD4LMNAMAPT | |
| SCHEMBL3466437 | 0.76 | DRD2 (0.43) | DRD3DRD2DRD4LMNAMAPT | |
| SCHEMBL3466440 | 0.76 | DRD2 (0.43) | DRD3DRD2DRD4LMNAMAPT | |
| SCHEMBL29507943 | 0.76 | DRD2 (0.46) | DRD3DRD2DRD4PSEN1PSEN2 | |
| SCHEMBL1640115 | 0.76 | DRD2 (0.46) | DRD3DRD2DRD4PSEN1PSEN2 | |
| SCHEMBL3468194 | 0.76 | DRD2 (0.46) | DRD3DRD2DRD4PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1038449-A | Antiarrhythmics | PFIZER LTD (GB) | 1990-01-03 | — | — | CN | claimed |
| CN-1038449-A | Antiarrhythmics | PFIZER LTD (GB) | 1990-01-03 | — | — | CN | disclosed |