Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CHIT1 | Q13231 | 3/20 | 0.37 |
| ▸ | CHIA | Q9BZP6 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716394 | 0.85 | HRH3 (0.41) | SIGMAR1DRD2DRD3DRD4GRIN2B | |
| SCHEMBL3467135 | 0.82 | DRD2 (0.43) | DRD2DRD3DRD4 | |
| SCHEMBL3466440 | 0.82 | DRD2 (0.43) | DRD2DRD3DRD4 | |
| SCHEMBL3466437 | 0.82 | DRD2 (0.43) | DRD2DRD3DRD4 | |
| SCHEMBL9776938 | 0.81 | GRIN2B (0.54) | DRD2DRD3DRD4GRIN2B | |
| SCHEMBL9769468 | 0.79 | TDP1 (0.39) | DRD2DRD3DRD4 | |
| Aniline SCHEMBL27296362 | 0.77 | DRD3 (0.46) | SIGMAR1DRD2DRD3DRD4GRIN2B | |
| SCHEMBL1640115 | 0.76 | DRD2 (0.46) | SIGMAR1DRD2DRD1DRD3DRD4 | |
| SCHEMBL29507943 | 0.76 | DRD2 (0.46) | SIGMAR1DRD2DRD1DRD3DRD4 | |
| SCHEMBL3468194 | 0.76 | DRD2 (0.46) | SIGMAR1DRD2DRD1DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1038449-A | Antiarrhythmics | PFIZER LTD (GB) | 1990-01-03 | — | — | CN | claimed |
| EP-0286278-A1 | Indanamine derivatives useful as antiarrhythmic agents | Pfizer Limited (GB) | 1988-10-12 | — | — | EP | claimed |
| US-5006561-A | Indane sulfonamide anti-arrhythmic agents and use | PFIZER INC. (US) | 1991-04-09 | — | — | US | disclosed |
| CN-1038449-A | Antiarrhythmics | PFIZER LTD (GB) | 1990-01-03 | — | — | CN | disclosed |
| EP-0286278-A1 | Indanamine derivatives useful as antiarrhythmic agents | Pfizer Limited (GB) | 1988-10-12 | — | — | EP | disclosed |