Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27501737 | 0.81 | CHRNB4 (0.33) | — | |
| SCHEMBL27499691 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2NPSR1LMNANPC1TP53 | |
| SCHEMBL27320266 | 0.77 | CHRNB4 (0.39) | SMN1; SMN2LMNATP53MEN1KMT2A | |
| SCHEMBL27528752 | 0.75 | ALDH1A1 (0.35) | SMN1; SMN2NPSR1LMNANPC1TP53 | |
| SCHEMBL27312472 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1LMNANPC1TP53 | |
| SCHEMBL27517106 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2NPSR1LMNANPC1TP53 | |
| SCHEMBL27520107 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2NPSR1LMNANPC1TP53 | |
| SCHEMBL27579973 | 0.70 | — | — | |
| SCHEMBL11559838 | 0.68 | NOTUM (0.36) | SMN1; SMN2NPSR1LMNANPC1TP53 | |
| SCHEMBL9849606 | 0.67 | KMT2A (0.40) | SMN1; SMN2LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032479-A | Replace azoles and its method for making of piperazine compounds and weeding purpose | SCHERING AG (DE) | 1989-04-26 | — | — | CN | disclosed |