Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499691 | 0.79 | SMN1; SMN2 (0.40) | ALDH1A1NPSR1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL27312472 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1NPSR1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL27301133 | 0.75 | SMN1; SMN2 (0.36) | ALDH1A1NPSR1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL27590523 | 0.74 | BCHE (0.30) | — | |
| SCHEMBL27312907 | 0.74 | MTNR1A (0.41) | ALDH1A1MTNR1AMEN1KMT2A | |
| SCHEMBL27570669 | 0.73 | MTNR1A (0.40) | ALDH1A1MTNR1AMEN1KMT2A | |
| SCHEMBL27520107 | 0.70 | SMN1; SMN2 (0.38) | ALDH1A1NPSR1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL27517106 | 0.70 | SMN1; SMN2 (0.41) | ALDH1A1NPSR1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL1764705 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL10978442 | 0.64 | HTT (0.58) | ALDH1A1MTNR1ASMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1197863-C | NOvel octahydro-2H-pyridino-[1,2-a] pyrazine compound, its prepn. process and medicinal compound contg. them | SERVIER LAB (FR) | 2005-04-20 | — | — | CN | disclosed |
| CN-1397557-A | NOvel octahydro-2H-pyridino-[1,2-a] pyrazine compound, its prepn. process and medicinal compound contg. them | SAVOIREN LAB (FR) | 2003-02-19 | — | — | CN | disclosed |