Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2708451 | 0.84 | SLC6A4 (0.51) | SLC6A4SLC6A3NPC1CASP3RAB9A | |
| SCHEMBL30301996 | 0.84 | SLC6A4 (0.51) | SLC6A4SLC6A3NPC1CASP3RAB9A | |
| SCHEMBL18281745 | 0.83 | CES2 (0.53) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL15273593 | 0.83 | SLC6A4 (0.45) | SLC6A4SLC6A3NPC1CASP3RAB9A | |
| SCHEMBL27736558 | 0.82 | AR (0.45) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL25108817 | 0.81 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL21807118 | 0.81 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2FFAR4CYP1A2 | |
| SCHEMBL27634442 | 0.80 | KEAP1 (0.36) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL16954819 | 0.80 | SLC6A4 (0.47) | SLC6A4SLC6A3NPC1CASP3RAB9A | |
| SCHEMBL23729962 | 0.80 | KEAP1 (0.52) | SLC6A4SLC6A3NPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032203-C | Process for preparing substituted 2-pyridones and pyrid-2-thiones | BAYER AG (DE) | 1996-07-03 | — | — | CN | disclosed |
| CN-1043501-A | Prepare the method that replaces 2-pyridone and pyridine-2-thioketones | BAYER AG (DE) | 1990-07-04 | — | — | CN | disclosed |