Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PRNP | P04156 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143585 | 0.85 | SMN1; SMN2 (0.48) | POLBPRNPALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23956928 | 0.77 | KIF11 (0.58) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8079696 | 0.75 | HSD11B1 (0.52) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21447568 | 0.75 | HSD11B1 (0.52) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5972547 | 0.75 | CYP2C19 (0.61) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL313012 | 0.73 | POLB (0.55) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8354123 | 0.73 | GAA (0.48) | POLBPRNPALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2027600 | 0.73 | LMNA (0.59) | POLBPRNPALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5972813 | 0.73 | SMN1; SMN2 (0.51) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10334914 | 0.72 | POLB (0.50) | POLBALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049803-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR TREATMENT OF HERPES VIRUSES | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2024049803-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR TREATMENT OF HERPES VIRUSES | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-03-07 | — | — | WO | disclosed |