Triethylene Glycol

Triethylene Glycol

SCHEMBL273034

CC(=O)O.COC.OCCOCCOCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Triethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 1/20 0.31
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
TSHR P16473 6/20 0.53
MAPK1 P28482 1/20 0.53
THRB P10828 2/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 6/20 0.43
FFAR3 O14843 1/20 0.37
LCK P06239 1/20 0.37
FYN P06241 1/20 0.37
HSD17B10 Q99714 2/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ADRB3 P13945 1/20 0.31
TP53 P04637 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL1561767 0.97 TSHR (0.56) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL994880 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Acetic Acid SCHEMBL21878891 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL28411928 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL27352527 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Pentaethylene Glycol SCHEMBL9614725 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL7049732 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Acetic Acid SCHEMBL21878939 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Acetic Acid SCHEMBL28250665 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL5632111 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4347062-A Complexes of high iron content soluble in organic media and usable as combustion additives in liquid fuels INSTITUT FRANCAIS DU PETROLE (FR) 1982-08-31 US claimed
US-20260125594-A1 QUANTUM DOT-CONTAINING COMPOSITION AND METHOD FOR PRODUCING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-05-07 US disclosed
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
EP-4715465-A1 MULTILAYER BODY, METHOD FOR PRODUCING MULTILAYER BODY, AND PHOTOSENSITIVE SURFACE MODIFIER Nissan Chemical Corporation (JP) 2026-03-25 EP disclosed
CN-121586750-A Composition for forming silicon-containing underlayer film for directional self-assembly 日产化学株式会社 2026-02-27 CN disclosed
EP-4679175-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM Nissan Chemical Corporation (JP) 2026-01-14 EP disclosed
US-20250377596-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-12-11 US disclosed
US-20250362609-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING POLYFUNCTIONAL SULFONIC ACID NISSAN CHEMICAL CORPORATION (JP) 2025-11-27 US disclosed
US-20250355357-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-11-20 US disclosed
US-20250348001-A1 METHOD FOR PRODUCING LAMINATE AND METHOD FOR PRODUCING SEMICONDUCTOR ELEMENT NISSAN CHEMICAL CORPORATION (JP) 2025-11-13 US disclosed
US-20050131091-A1 Process for producing synthetic resin foam, blowing agent and premix DAIKIN INDUSTRIES, LTD. (JP) 2005-06-16 US disclosed
US-20050043422-A1 Process for producing synthetic resin foam DAIKIN INDUSTRIES, LTD. (JP) 2005-02-24 US disclosed
US-6849385-B2 Photosensitive resin composition, process of forming patterns with the same, and electronic components HITACHI CHEMICAL CO., LTD. (JP) 2005-02-01 US disclosed
EP-1498439-A1 PROCESS FOR PRODUCING SYNTHETIC RESIN FOAM, BLOWING AGENT, AND PREMIX Daikin Industries, Ltd. (JP) 2005-01-19 EP disclosed
US-20040180286-A1 Photosensitive resin composition, process of forming patterns with the same, and electronic components HITACHI CHEMICAL CO., LTD. (JP) 2004-09-16 US disclosed
EP-1457506-A1 PROCESS FOR PRODUCING SYNTHETIC RESIN FOAM Daikin Industries, Ltd. (JP) 2004-09-15 EP disclosed
CN-1522388-A Photosensitive resin composition, method for producing pattern and electronic parts 日立化成工业株式会社 2004-08-18 CN disclosed
US-6596446-B2 Used in in printing inks BAYER AKTIENGESELLSCHAFT (DE) 2003-07-22 US disclosed
US-20020034696-A1 Organic pigments in color filters of liquid crystal display LANXESS DEUTSCHLAND GMBH (DE) 2002-03-21 US disclosed
US-4347062-A Complexes of high iron content soluble in organic media and usable as combustion additives in liquid fuels INSTITUT FRANCAIS DU PETROLE (FR) 1982-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM SRSF1, MACF1, SRPK1 ADRB2 4696/4885MEN1 2480/4885KMT2A 111/4885
US-20260125594-A1 QUANTUM DOT-CONTAINING COMPOSITION AND METHOD FOR PRODUCING THE SAME ITGA6, STRA6, ILK ADRB2 3758/4885MEN1 4558/4885KMT2A 1830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.